@article {1236,
	title = {Insights into Retinal Development Using Live Imaging in Female Carriers of Choroideremia.},
	journal = {Ophthalmic Surg Lasers Imaging Retina},
	volume = {50},
	year = {2019},
	month = {2019 May 01},
	pages = {e158-e162},
	abstract = {<p>Lineage tracing can provide key insights into the development of tissues, such as the retina. Yet it is not possible to manipulate human cells during embryogenesis. The authors observed a distinct phenotype in female carriers of X-linked disorders, in particular, carriers of choroideremia caused by mutations in CHM, encoding Rab escort protein-1. The authors found that X chromosome inactivation provides a method for retinal lineage tracing in human patients. Live imaging of female carriers displays a developmental pattern that is different within the peripheral retina compared with the posterior retina and provides important insights into the development and migration of retinal cells. [Ophthalmic Surg Lasers Imaging Retina. 2019;50:e158-e162.].</p>},
	issn = {2325-8179},
	doi = {10.3928/23258160-20190503-15},
	author = {Wert, Katherine J and Bakall, Benjamin and Bassuk, Alexander G and Tsang, Stephen H and Mahajan, Vinit B}
}
