@article {1901,
	title = {A protocol to inject ocular drug implants into mouse eyes.},
	journal = {STAR Protoc},
	volume = {3},
	year = {2022},
	month = {2022 03 18},
	pages = {101143},
	abstract = {<p>Ocular drug implants (ODIs) are beneficial for treating ocular diseases. However, the lack of a robust injection approach for small-eyed model organisms has been a major technical limitation in developing ODIs. Here, we present a cost-effective, minimally invasive protocol to deliver ODIs into the mouse vitreous called Mouse Implant Intravitreal Injection (MI3). MI3 provides two alternative surgical approaches (air-pressure or plunger) to deliver micro-scaled ODIs into milli-scaled eyes, and expands the preclinical platforms to determine ODIs\&$\#$39; efficacy, toxicity, and pharmacokinetics. For complete details on the use and execution of this protocol, please refer to Sun et\&nbsp;al. (2021).</p>
},
	keywords = {Animals, Drug Implants, Intravitreal Injections, Mice, Vitreous Body},
	issn = {2666-1667},
	doi = {10.1016/j.xpro.2022.101143},
	author = {Lin, Cheng-Hui and Sun, Young Joo and Lee, Soo Hyeon and Mujica, Elena M and Kunchur, Caitlin R and Wu, Man-Ru and Yang, Jing and Jung, Youn Soo and Chiang, Bryce and Wang, Sui and Mahajan, Vinit B}
}
